Blood and Tissue Nematodes of Man

Larva migrans:
-Migran of larval nematodes in unsuitable host.
-Unable to complete their normal development.
-Distributed in the host tissue & eventually dies.
1.Visceral: larvae of nonhuman ascarids.
2.Cutaneous: cat or dog hookworms, dog filariform larva.
3.Subcutaneous & Visceral: spiruroid larva.

Visceral larva migrans (VLM):
-Extraintestinal migration of larval nematodes of lower animals.
-Invading tissues:
--Liver, lung, eye, brain, spinal cord, heart, kidney, lymphn node.
-Toxocara canis (primary causative agent)

Cutaneous larva migrans (CLM):
-Life cycle:
--Dog -> Final Host
--Human -> Foreign Host
-Epidemiology: Cosmopolitan.
-Clinical aspect:
--Linear inflammatory lesion of skin -> creeping eruption.
--Secondary bacterial infections.
-Treatment:
--Thiabendazole: 25mg/Kg BW, b.i.d for 5 days